Products for Research Use Only
RegisterLogin

EeAChE-IN-3

CAT: 0804-HY-162681Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-162681Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EeAChE-IN-3 (compound YS3g) is an orally active, potent EeAChE and IL-6 inhibitor with IC50s of 0.54 μM, 0.49 μM, 8.54 μM and 0.57 μM for EeAChE, RatAChE, RatBuChE and IL-6, respectively. eeAChE-IN-3 improves STZ (Streptozotocin; HY-13753) -induced learning and memory impairment in mice. eeAChE-IN-3 has the potential for Alzheimer's disease (AD) research[1].
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/eeache-in-3.html
Smiles
O=C1C2=C(OC)C=C(OC)C=C2OC(CCCNN3CCNCC3)=C1
Molecular Formula
C18H25N3O4
Molecular Weight
347.41
References & Citations
[1]Shivam Mishra, et al.Chromone hybrids as interleukin-6 and acetylcholinesterase inhibitor for treatment of Alzheimer's disease: Design, docking, synthesis and evaluation. European Journal of Medicinal Chemistry Reports. Volume 12, December 2024, 100180.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; IL-6

Related Products

CatalogName
HY-132904EeAChE-IN-2
HY-132903EeAChE-IN-1
HY-157394EeAChE/eqBuChE-IN-1
HY-W081226-013,3,3-Trifluoropropionyl chloride
HY-W127810-013,3',3''-Nitrilotripropionic Acid
HY-W4403031,1',3,3,3',3'-Hexamethylindotricarbocyanine (perchlorate)
HY-D1075-011,1',3,3,3',3'-Hexamethylindodicarbocyanine (iodide)
HY-W1146693- (3- (3-Ethoxy-3-oxopropoxy) propoxy) propanoicacid
HY-178928KV1.3-IN-3
HY-176547FGFR2/3-IN-3

Alternative Products

CatalogName
T210297-01EeAChE-IN-3
T63889-01EeAChE-IN-1
T72983-01EeAChE-IN-2
T86340-01EeAChE/eqBuChE-IN-1
PC68253,3,3-Trifluoropropyl 3,3,3-trifluoropropanoate
QMC01729-013- (3,3,3-Trifluoropropoxy) pyridine
JFC42829-013- (3,3,3-Trifluoropropyl) aniline
sc-2604333- (3,3,3-Trifluoropropyl) heptamethyltrisiloxane
PDC53711-013- (3,3,3-Trifluoropropoxy) piperidine
NU-456L3',3',3'-cAAG

Popular Products