Sinapaldehyde

• Description :

  Sinapaldehyde is a methoxyphenol and a selective COX-2 inhibitor (IC50: 47.8 µM) that can be extracted from various plants. Sinapaldehyde has antibacterial, anti-inflammatory, and antioxidant activities. Sinapaldehyde can scavenge DPPH free radicals (IC50: 172 μM) . Sinapaldehyde is active against both Gram-negative and Gram-positive bacteria[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Bacterial; COX; Interleukin Related; JNK; NO Synthase; PERK; Reactive Oxygen Species (ROS)

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/sinapaldehyde.html

• Purity :

  99.71

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C/C=C/C1=CC(OC)=C(O)C(OC)=C1

• Molecular Formula :

  C11H12O4

• Molecular Weight :

  208.21

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  Rhodamnia Dumetorum

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  COX-2; IL-6

• CAS Number :

  [4206-58-0]