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PC Antibody

CAT: 0013-GTR18124203Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18124203Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PC Antibody
Product Name Alternative
PC, pyruvate carboxylase, PCB
UniProt
P11498
Reactivity
Human, Mouse
Immunogen
The immunogen for this antibody is: C-KFKEVKKAYVEANQ
Target
PC
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Approx 150kDa band observed in Mouse Liver lysates (calculated MW of 130kDa according to NP_000911.2, NP_001035806.1 and NP_071504.2) . Recommended concentration: 0.03-0.1μg/mL. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Liver. Recommended concentration: 5μg/mL.
Prediction Reactivity
Bovine, Canine, Porcine, Rat
Tested Applications
ELISA, IHC, WB
NCBI Accession Number
NP_000911.2, NP_071504.2, NP_001035806.1
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

UniProtKB · P11498

Pyruvate carboxylase, mitochondrial

PYC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11498
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
6.4.1.1
Processing
Precursor
Secondary accessions
B4DN00, Q16705
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingBiotinManganeseMetal-bindingNucleotide-bindingPyruvate

Disease

Disease variant

Biological process

GluconeogenesisLipid biosynthesisLipid metabolism

Molecular function

LigaseMultifunctional enzyme

Cellular component

Mitochondrion

Domain

Transit peptide

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