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SOCS4 Antibody

CAT: 0013-GTR18124078Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18124078Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SOCS4 Antibody
Product Name Alternative
SOCS4, suppressor of cytokine signaling 4, DKFZp686J1568, SOCS7, SH2 domain containing SOCS box protein, suppressor of cytokine signaling 7
UniProt
Q8WXH5
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-SKVRVLRIDAPEQQ
Target
SOCS4
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments in Human and Rodent Brain lysates and in lysates of cell lines NIH3T3, A431 and HeLa gave no specific signal but low background (at antibody concentration up to 1μg/mL) . We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?Immunohistochemistry:In paraffin embedded Human Pancreas shows cytoplasm staining on select beta cells in islet of Langerhans. Recommended concentration, 3-6μg/mL.
Prediction Reactivity
Bovine, Porcine
Tested Applications
ELISA, IHC
NCBI Accession Number
NP_955453.1, NP_543143.1
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

UniProtKB · Q8WXH5

Suppressor of cytokine signaling 4

SOCS4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WXH5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SOCS4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SOCS-4
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Growth regulationUbl conjugation pathway

Domain

SH2 domain

Molecular function

Signal transduction inhibitor

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MBS9403646-01SOCS4 antibody

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