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L162389

CAT: 0804-HY-101618-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101618-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
CAS Number
169281-53-2
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/L162389.html
Solubility
10 mM in DMSO
Smiles
O=C(OCCCC)NS(=O)(C1=CC=C(CCC)C=C1C2=CC=C(CN3C(CC)=NC4=C(C)C=C(C)N=C43)C=C2)=O
Molecular Formula
C31H38N4O4S
Molecular Weight
562.72
References & Citations
[1]Perlman S, et al. Dual agonistic and antagonistic property of nonpeptide angiotensin AT1 ligands: susceptibility to receptor mutations. Mol Pharmacol. 1997 Feb;51 (2) :301-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AT1 Receptor