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SCNN1G Antibody

CAT: 0013-GTR18123760Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18123760Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SCNN1G Antibody
Product Name Alternative
SCNN1G, sodium channel, nonvoltage-gated 1, gamma, ENaCg, ENaCgamma, PHA1, SCNEG, ENaC gamma subunit, amiloride-sensitive epithelial sodium channel gamma subunit
UniProt
P51170
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-SNQLTDTQMLDE
Target
SCNN1G
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Signal Transduction
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave an approx 140kDa band in Human Breast cancer and Colon lysates after 1μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 74.3kDa according to NP_001030.2. The 140kDa band was successfully blocked by incubation with the immunizing peptide.Immunohistochemistry:Paraffin embedded Human Colon. Recommended concentration: 4μg/mL.
Tested Applications
ELISA, IHC
NCBI Accession Number
NP_001030.2
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

UniProtKB · P51170

Epithelial sodium channel subunit gamma

SCNNG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P51170
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCNN1G
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ENaC subunit gamma, ENaCG, Epithelial Na(+) channel subunit gamma, Gamma-ENaC
EC number
—
Processing
—
Secondary accessions
P78437, Q6PCC2, Q93023, Q93024, Q93025, Q93026, Q93027, Q96TD2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Molecular function

Ion channelSodium channel

Biological process

Ion transportSodium transportTransport

Ligand

Sodium

Domain

TransmembraneTransmembrane helix

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