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Mouse M-CSF Recombinant Protein

CAT: 0519-R00620Size: 5 µgDry Ice: NoHazardous: No
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CAT#:0519-R00620Size:5 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Macrophage colony-stimulating factor (M-CSF), also known as CSF-1, is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Mouse M-CSF Recombinant Protein is purified Macrophage colony-stimulating factor (M-CSF, CSF-1) produced in yeast.
Synonyms
Macrophage colony-stimulating factor 1; CSF-1; MCSF; Processed macrophage colony-stimulating factor 1; Csf1; Csfm
Gene Name
CSF1
UniProt
P07141
Source
Yeast
Sequence
[object Object]
Applications
Cell Culture
Field of Research
Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Macrophage/Inflammation, Vascular Inflammation
Purification
Ion-exchange chromatography.
Bioactivity
In testing.
Form
Lyophilized
Function
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Subcellular Location
Cell membrane; Single-pass type I membrane protein.

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