Mouse IL-1 beta Recombinant Protein

• Description:

  IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Mouse IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

• Synonyms:

  Interleukin-1 beta; IL-1 beta; Il1b

• Gene Name:

  IL1B

• UniProt:

  P10749

• Tissue Specificity:

  Expressed in activated macrophages (at protein level) .

• Source:

  Yeast

• Sequence:

  [object Object]

• Applications:

  Cell Culture

• Field of Research:

  Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Metabolism, Obesity, Vascular Inflammation

• Purification:

  Ion-exchange chromatography.

• Bioactivity:

  In testing.

• Form:

  Lyophilized

• Function:

  Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Cytoplasm, cytosol.