IRS-1 (Phospho-Tyr896) Colorimetric Cell-Based ELISA Kit

• Description:

  The IRS-1 (Phospho-Tyr896) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IRS-1 (Phospho-Tyr896) protein expression profile in cells. The kit can be used for measuring the relative amounts of IRS-1 (Phospho-Tyr896) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IRS-1 (Phospho-Tyr896) .

• Synonyms:

  Insulin receptor substrate 1; IRS-1; IRS1

• Gene Name:

  IRS1

• UniProt:

  P35568

• Reactivity:

  Human, Mouse, Rat

• Applications:

  ELISA

• Detection Range:

  > 5000 cells/well

• Function:

  May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity) .

• Molecular Weight:

  131591 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Insulin receptor substrate 1