IL-13Ralpha1 (Phospho-Tyr405) Colorimetric Cell-Based ELISA Kit

• Description:

  The IL-13Ralpha1 (Phospho-Tyr405) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IL-13Ralpha1 (Phospho-Tyr405) protein expression profile in cells. The kit can be used for measuring the relative amounts of IL-13Ralpha1 (Phospho-Tyr405) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IL-13Ralpha1 (Phospho-Tyr405) .

• Synonyms:

  CD213a1 antigen; I13R1; IL- 13RA-1; IL-13R alpha 1; IL-13R-alpha-1; IL13RA; IL13RA1; Interleukin-13 receptor alpha-1 chain precursor

• Gene Name:

  IL13RA1

• UniProt:

  P78552

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Ubiquitous. Highest levels in heart, liver, skeletal muscle and ovary; lowest levels in brain, lung and kidney. Also found in B-cells, T-cells and endothelial cells.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Binds with low affinity to interleukin-13 (IL13) . Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

• Molecular Weight:

  48760 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Interleukin-13 receptor subunit alpha-1

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.