PKA-R2beta (Phospho-Ser113) Colorimetric Cell-Based ELISA Kit

• Description:

  The PKA-R2beta (Phospho-Ser113) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PKA-R2beta (Phospho-Ser113) protein expression profile in cells. The kit can be used for measuring the relative amounts of PKA-R2beta (Phospho-Ser113) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PKA-R2beta (Phospho-Ser113) .

• Synonyms:

  KAP3; PKA R2-beta; PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory chain

• Gene Name:

  PRKAR2B

• UniProt:

  P31323

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

• Molecular Weight:

  46302 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  CAMP-dependent protein kinase type II-beta regulatory subunit

• Subcellular Location:

  Cytoplasm. Cell membrane. Colocalizes with PJA2 in the cytoplasm and at the cell membrane.