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EIF4B (Phospho-Ser422) Colorimetric Cell-Based ELISA Kit

CAT: 0519-EKC2152Size: 1 Kit, Containing two 96 Well Plates and all necessary reagentsDry Ice: NoHazardous: No
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CAT#:0519-EKC2152Size:1 Kit, Containing two 96 Well Plates and all necessary reagents
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The eIF4B (Phospho-Ser422) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor eIF4B (Phospho-Ser422) protein expression profile in cells. The kit can be used for measuring the relative amounts of eIF4B (Phospho-Ser422) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on eIF4B (Phospho-Ser422) .
Synonyms
Eukaryotic translation initiation factor 4B; IF4B; eIF-4B
Gene Name
EIF4B
UniProt
P23588
Reactivity
Human, Mouse
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Molecular Weight
69151 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Eukaryotic translation initiation factor 4B

UniProtKB · P23588

Eukaryotic translation initiation factor 4B

IF4B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23588
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EIF4B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
eIF-4B
EC number
—
Processing
—
Secondary accessions
B4DS13, Q4G0E3, Q53HQ2, Q6GPH5, Q6IB46, Q8WYK5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Molecular function

Initiation factorRNA-binding

Biological process

Protein biosynthesis

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