Opioid Receptor-delta (Phospho-Ser363) Colorimetric Cell-Based ELISA Kit

• Description:

  The Opioid Receptor-delta (Phospho-Ser363) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Opioid Receptor-delta (Phospho-Ser363) protein expression profile in cells. The kit can be used for measuring the relative amounts of Opioid Receptor-delta (Phospho-Ser363) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Opioid Receptor-delta (Phospho-Ser363) .

• Synonyms:

  Delta-opioid receptor; Delta-type opioid receptor; K56; MSL-2; OPRD; OPRD1; Opioid receptor delta

• Gene Name:

  OPRD1

• UniProt:

  P41143

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Detected in oocytes (at protein level) . Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

• Molecular Weight:

  40369 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Delta-type opioid receptor

• Subcellular Location:

  Cell membrane; Multi- pass membrane protein.