MMP-19 Colorimetric Cell-Based ELISA Kit

• Description:

  The MMP-19 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MMP-19 protein expression profile in cells. The kit can be used for measuring the relative amounts of MMP-19 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MMP-19.

• Synonyms:

  Matrix metalloproteinase-19; MMP-19; Matrix metalloproteinase RASI; MMP-18; MMP19; MMP18; RASI

• Gene Name:

  MMP19

• UniProt:

  Q99542

• Reactivity:

  Human, Mouse

• Tissue Specificity:

  Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients (PubMed:8920941) .

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease) . May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.

• Molecular Weight:

  57357 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Matrix metalloproteinase-19

• Subcellular Location:

  Secreted, extracellular space, extracellular matrix.