Glucagon Colorimetric Cell-Based ELISA Kit

• Description:

  The Glucagon Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Glucagon protein expression profile in cells. The kit can be used for measuring the relative amounts of Glucagon in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Glucagon.

• Synonyms:

  Glucagon; GCG

• Gene Name:

  GCG

• UniProt:

  P01275

• Reactivity:

  Human, Mouse, Rat

• Tissue Specificity:

  Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP-1 and GLP-2 are also secreted in selected neurons in the brain.

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.

• Molecular Weight:

  20909 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Glucagon

• Subcellular Location:

  Secreted.