Adrenergic Receptor beta2 Colorimetric Cell-Based ELISA Kit

• Description:

  The Adrenergic Receptor beta2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Adrenergic Receptor beta2 protein expression profile in cells. The kit can be used for measuring the relative amounts of Adrenergic Receptor beta2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Adrenergic Receptor beta2.

• Synonyms:

  Beta-2 adrenergic receptor; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; ADRB2; ADRB2R; B2AR

• Gene Name:

  ADRB2

• UniProt:

  P07550

• Reactivity:

  Human

• Applications:

  ELISA

• Sample Type:

  Cell lines

• Detection Range:

  > 5000 cells/well

• Function:

  Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

• Molecular Weight:

  46459 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at 4°C for up to 6 months.

• Other Gene Names:

  Beta-2 adrenergic receptor

• Subcellular Location:

  Cell membrane; Multi- pass membrane protein. Early endosome. Colocalizes with VHL at the cell membrane (PubMed:19584355) . Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) .