Anti-Phospho-Tyrosine Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-Phospho-Tyrosine Rabbit Monoclonal Antibody catalog # PT0005. Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Histone H2A.2; HTA2; H2A2; YBL003C; YBL0103

• Gene Name:

  Histone H2A.2

• UniProt:

  P04912

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from Phosphotyrosine

• Clonality:

  Monoclonal

• Clone:

  Clone: AAOI-20

• Tissue Specificity:

  Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

• Applications:

  WB, ICC, IF, IP, Flow Cytometry

• Field of Research:

  Epigenetics and Nuclear Signaling, Histones

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Function:

  Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. .

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  WB 1:500-1:2000
  ICC/IF 1:50-1:200
  IP 1:50
  FC 1:50

• Other Gene Names:

  Tyrosine

• Subcellular Location:

  Nucleus. Chromosome.

• Protein Name:

  Synapsin-1