Anti-Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Monoclonal Antibody

• Background:

  This monoclonal antibody recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

• Description:

  Boster Bio Anti-Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 Monoclonal Antibody (Catalog # M07518) . Tested in Flow Cytometry, WB, IHC applications. This antibody reacts with Human, Mouse, Rat, Rabbit, Dog.

• Synonyms:

  Cadherin-16; Kidney-specific cadherin; Ksp-cadherin; CDH16; UNQ695/PRO1340

• Gene Name:

  CDH16

• UniProt:

  O75309

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat, Rabbit, Dog

• Immunogen:

  Recombinant full-length human CDH16 protein

• Clonality:

  Monoclonal

• Clone:

  Clone: Clone: rCDH16/1071

• Tissue Specificity:

  Kidney specific.

• Applications:

  Flow Cytometry, WB, IHC

• Field of Research:

  Cadherins, Cell Adhesion, Cytoskeleton/ECM, Signal Transduction

• Purification:

  200ug/ml of recombinant monoclonal antibody purified by Protein A/G.

• Concentration:

  Purified antibody with BSA and azide at 200ug/ml

• Form:

  Liquid

• Function:

  Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

• Molecular Weight:

  89923 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Fragment:

  IgG1, kappa

• Other Gene Names:

  Cadherin-16

• Subcellular Location:

  Cell Surface and Cytoplasmic