Anti-Napsin A (Lung Adenocarcinoma Marker) NAPSA Monoclonal Antibody

• Background:

  Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

• Description:

  Boster Bio Anti-Napsin A (Lung Adenocarcinoma Marker) NAPSA Monoclonal Antibody (Catalog # M05685-1) . Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human.

• Synonyms:

  Napsin-A;3.4.23.-; Aspartyl protease 4; ASP4; Asp 4; Napsin-1; TA01/TA02; NAPSA; NAP1, NAPA

• Gene Name:

  NAPSA

• UniProt:

  O96009

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)

• Clonality:

  Monoclonal

• Clone:

  Clone: Clone: NAPSA/1238 + NAPSA/1239

• Tissue Specificity:

  Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes.

• Applications:

  Flow Cytometry, IF, WB, IHC

• Field of Research:

  Cell Biology, Cell Type Markers, Proteolysis/Ubiquitin, Proteolytic Enzymes, Tags & Cell Markers, Tumor Associated

• Purification:

  200ug/ml of antibody purified from rabbit anti-serum by Protein A.

• Concentration:

  Purified antibody with BSA and azide at 200ug/ml

• Form:

  Liquid

• Function:

  May be involved in processing of pneumocyte surfactant precursors.

• Molecular Weight:

  45387 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Fragment:

  IgG, kappa

• Other Gene Names:

  Napsin-A

• Subcellular Location:

  Cytoplasmic