Anti-Acetyl-Histone H2A.Z (Lys4) H2AFZ Rabbit Monoclonal Antibody, Clone#RM221

• Description:

  Boster Bio Anti-Acetyl-Histone H2A.Z (Lys4) H2AFZ Rabbit Monoclonal Antibody, Clone#RM221 (Catalog # M04816) . Tested in WB, ELISA, Luminex, ICC applications. This antibody reacts with Human, Vertebrates.

• Synonyms:

  Histone H2A.Z; H2A/z; H2AFZ; H2AZ

• Gene Name:

  H2AFZ

• UniProt:

  P0C0S5

• Host:

  Rabbit

• Reactivity:

  Human, Vertebrates

• Cross Reactivity:

  This antibody reacts to Histone H2A.Z acetylated at Lysine 4 (K4ac) . No cross-reactivity with non-modified Lysine 4 or other acetylated Lysines in histone H2A

• Immunogen:

  An acetyl-peptide corresponding to Acetyl-Histone H2A.Z (Lys4)

• Clonality:

  Monoclonal

• Clone:

  Clone: RM221

• Applications:

  WB, ELISA, Luminex, ICC

• Field of Research:

  2339, Epigenetics and Nuclear Signaling, Histones

• Purification:

  Protein A affinity purified from an animal origin-free culture supernatant

• Concentration:

  1 mg/mL

• Form:

  Liquid

• Function:

  Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.

• Molecular Weight:

  13553 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Other Gene Names:

  Histone H2A.Z

• Subcellular Location:

  Nucleus. Chromosome.