Anti-TRIM29 (Lung Squamous Cell Carcinoma Marker) Monoclonal Antibody

• Background:

  This monoclonal antibody recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29) . It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.

• Description:

  Boster Bio Anti-TRIM29 (Lung Squamous Cell Carcinoma Marker) Monoclonal Antibody (Catalog # M04472) . Tested in WB applications. This antibody reacts with Human.

• Synonyms:

  Tripartite motif-containing protein 29; Ataxia telangiectasia group D-associated protein; TRIM29; ATDC

• Gene Name:

  TRIM29

• UniProt:

  Q14134

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein

• Clonality:

  Monoclonal

• Clone:

  Clone: Clone: TRIM29/1042

• Tissue Specificity:

  Expressed in placenta, prostate and thymus. .

• Applications:

  WB

• Field of Research:

  Cell Biology, Cell Cycle, Cell Differentiation, DNA/Nucleotides, DNA/RNA, Domain Families, Epigenetics and Nuclear Signaling, Hlh/Leucine Zipper, Transcription, Transcription Factors, Zinc Finger

• Purification:

  200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.

• Concentration:

  Purified antibody with BSA and azide at 200ug/ml

• Form:

  Liquid

• Function:

  It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.

• Molecular Weight:

  65835 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Fragment:

  IgG2b, kappa

• Other Gene Names:

  Tripartite motif-containing protein 29

• Subcellular Location:

  Cell Surface and Cytoplasmic