Anti-CK18 (Cytokeratin-18) KRT18 Rabbit Monoclonal Antibody, Clone#RM279

• Description:

  Boster Bio Anti-CK18 (Cytokeratin-18) KRT18 Rabbit Monoclonal Antibody, Clone#RM279 (Catalog # M01357-3) . Tested in IHC, WB applications. This antibody reacts with Human.

• Synonyms:

  Keratin, type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18; KRT18; CYK18; PIG46

• Gene Name:

  KRT18

• UniProt:

  P05783

• Host:

  Rabbit

• Reactivity:

  Human

• Cross Reactivity:

  This antibody reacts to human CK18 (Cytokeratin-18) .

• Immunogen:

  A peptide corresponding to the N-terminus of human Cytokeratin-18.

• Clonality:

  Monoclonal

• Clone:

  Clone: RM279

• Tissue Specificity:

  Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.

• Applications:

  IHC, WB

• Field of Research:

  Cell Type Markers, Class I, Cytoskeleton, Cytoskeleton/ECM, ECM Proteins, Extracellular Matrix, Intermediate Filaments, Microtubules, Signal Transduction, Structures, Tumor Associated

• Purification:

  Protein A affinity purified from an animal origin-free culture supernatant

• Concentration:

  0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Function:

  Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity) . When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6) -mediated barrier protection.

• Molecular Weight:

  48058 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Other Gene Names:

  Keratin, type I cytoskeletal 18

• Subcellular Location:

  Cytoplasm, perinuclear region. Nucleus, nucleolus.