Anti-CD18 ITGB2 Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-CD18 ITGB2 Rabbit Monoclonal Antibody catalog # M00458. Tested in WB, IP applications. This antibody reacts with Human.

• Synonyms:

  Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD18; ITGB2; CD18, MFI7

• Gene Name:

  Integrin beta-2

• UniProt:

  P05107

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human CD18

• Clonality:

  Monoclonal

• Clone:

  Clone: AAIH-9

• Tissue Specificity:

  Highly expressed in placenta. Low expression in small intestine, liver and colon. .

• Applications:

  WB, IP

• Field of Research:

  Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Signal Transduction, Stem Cells

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. .

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  WB 1:500-1:2000
  IP 1:50

• Other Gene Names:

  ITGB2

• Subcellular Location:

  Membrane; Single-pass type I membrane protein.

• Protein Name:

  T-cell surface glycoprotein CD4