Anti-TBP/Tata Binding Protein Tbp Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-TBP/Tata Binding Protein Tbp Rabbit Monoclonal Antibody catalog # M00302. Tested in WB application. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit; TBP; GTF2D1, TF2D, TFIID

• Gene Name:

  TATA-box-binding protein

• UniProt:

  P20226

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human TBP

• Clonality:

  Monoclonal

• Clone:

  Clone: DOA-20

• Tissue Specificity:

  Widely expressed, with levels highest in the testis and ovary. .

• Applications:

  WB

• Field of Research:

  2339, Epigenetics and Nuclear Signaling, Pol II Transcription, Polymerase Associated Factors, Transcription

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. .

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  WB 1:1000-1:2000

• Other Gene Names:

  TBP

• Subcellular Location:

  Nucleus.

• Protein Name:

  P2X purinoceptor 1