Anti-TMEM30B/Cdc50B Antibody

• Background:

  Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate Probable. Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
  
  The MGC Project Team, Genome Res. 14:2121-2127(2004).
  Katoh Y., Oncol. Rep. 12:939-943(2004).

• Description:

  Boster Bio Anti-TMEM30B/Cdc50B Antibody (Catalog # A13764) . Tested in WB applications. This antibody reacts with Human.

• Synonyms:

  Cell cycle control protein 50B; P4-ATPase flippase complex beta subunit TMEM30B; Transmembrane protein 30B; TMEM30B; CDC50B

• Gene Name:

  TMEM30B

• UniProt:

  Q3MIR4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthesized peptide derived from internal of human TMEM30B.

• Clonality:

  Polyclonal

• Applications:

  WB

• Field of Research:

  Cell Biology

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Dilution:

  Western blotting: 1:500~1:3000

• Form:

  Liquid

• Function:

  Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable) . Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. .

• Molecular Weight:

  38941 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Cell cycle control protein 50B

• Subcellular Location:

  Cell membrane ; Multi-pass membrane protein .