Anti-ApoO Monoclonal Antibody

CAT: 0519-A09879Size: 100 µLDry Ice: NoHazardous: No
CAT#:0519-A09879Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boster Bio Anti-ApoO Monoclonal Antibody catalog # A09879. Tested in IHC, WB applications. This antibody reacts with Human, Mouse.
Synonyms
MIC
Gene Name
APOO
UniProt
Q9BUR5
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Purified recombinant fragment of ApoO expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 2F1
Tissue Specificity
Expressed in all tissues examined. Up- regulated in diabetic heart. .
Applications
WB, IHC
Purification
Ascitic fluid
Form
Liquid
Function
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979) . Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151) . Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP) -dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892) . .
Molecular Weight
22285 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
MICOS complex subunit MIC26
Subcellular Location
Mitochondrion inner membrane ; Single-pass membrane protein . Secreted . Mitochondrion . Golgi apparatus membrane . Endoplasmic reticulum membrane . Exists in three distinct forms: a glycosylated and secreted form, an ER/Golgi-resident form and a non-glycosylated mitochondrial form. .

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