Anti-Setdb2 Antibody

• Background:

  Setdb2 and the neighboring gene Phf11 were linked to familial atopy/ asthma and are in a "critical region" commonly deleted in CLL. Setdb2 is a candidate histone methyltransferase as a member of the Su (var) 3-9 family of SET domain-containing enzymes. Other predicted domains in Setdb2 include a methylcytosine binding domain and a large bifurcation domain interrupting the putative histone methyltransferase (SET) domain whose function is unknown. Anti-Setdb2 antibody is ideal for researchers interested in Cancer Research and Epigenetics Research.

• Description:

  Boster Bio Anti-Setdb2 Antibody (Catalog # A08290) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  Setdb2, Histone-lysine N-methyltransferase SETDB2, SET domain bifurcated 2, Setdb 2, Gm293

• Gene Name:

  SETDB2

• UniProt:

  Q8C267

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Setdb2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a full length protein corresponding to mouse Setdb2.

• Clonality:

  Polyclonal

• Applications:

  ELISA, WB

• Field of Research:

  Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Methylation

• Purification:

  This Protein A purified antibody is directed against mouse Setdb2. The product was purified from monospecific antiserum by Protein A affinity chromatography. Expect reactivity with Setdb2 from mouse and human sources. Reactivity against homologues from other sources is not known.

• Concentration:

  0.98 mg/mL by UV absorbance at 280 nm

• Form:

  Liquid (sterile filtered)

• Shipping Conditions:

  Due to dry ice shipping issues, this product is temporarily not available to distributors outside of the United States.

• Storage Conditions:

  Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.

• Fragment:

  IgG

• Applications Notes:

  Anti-Setdb2 antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80.6 kDa in size corresponding to Setdb2 by western blotting in the appropriate cell lysate or extract.