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Anti-CDCA7 Antibody

CAT: 0519-A07777Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A07777Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.

Prescott J.E., J. Biol. Chem. 276:48276-48284(2001).
Ota T., Nat. Genet. 36:40-45(2004).
Hillier L.W., Nature 434:724-731(2005).
Description
Boster Bio Anti-CDCA7 Antibody (Catalog # A07777) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Cell division cycle-associated protein 7; Protein JPO1; CDCA7; JPO1
Gene Name
CDCA7
UniProt
Q9BWT1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from internal of human CDCA7.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous with higher level in thymus and small intestine. Overexpressed in a large number of tumors, in blood from patients with acute myelogenous leukemia (AML) and in chronic myelogenous leukemia (CML) blast crisis. .
Applications
WB
Field of Research
Cancer, Epigenetics and Nuclear Signaling, Transcription, Tumor Biomarkers
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Western blotting: 1:500~1:3000
Form
Liquid
Function
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator. .
Molecular Weight
42573 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Cell division cycle-associated protein 7
Subcellular Location
Nucleus. Cytoplasm. Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163.

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