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Anti-PPP2R2B Antibody

CAT: 0519-A05805Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0519-A05805Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity By similarity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance By similarity.

Mayer R.E., Biochemistry 30:3589-3597(1991) [PubMed: 1849734].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
Schmutz J., Nature 431:268-274(2004) [PubMed: 15372022].
Description
Boster Bio Anti-PPP2R2B Antibody (Catalog # A05805) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Synonyms
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; PP2A subunit B isoform B55-beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2-beta; PP2A subunit B isoform beta; PPP2R2B
Gene Name
PPP2R2B
UniProt
Q00005
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from internal of human PPP2R2B.
Clonality
Polyclonal
Tissue Specificity
Brain.
Applications
WB
Field of Research
Neurodegenerative Disease, Neurology Process, Neuroscience, Protein Phosphorylation, Ser/Thr Phosphatases, Signal Transduction
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Western blotting: 1:500~1:3000
Form
Liquid
Function
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity) . Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity) . .
Molecular Weight
51710 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Subcellular Location
Isoform 1: Cytoplasm . Cytoplasm, cytoskeleton . Membrane .

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