Anti-TAB3/Map3K7Ip3 Antibody

• Description:

  Boster Bio Anti-TAB3/Map3K7Ip3 Antibody (Catalog# A05084) . Tested in WB application (s) . This antibody reacts with Human.

• Synonyms:

  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; Mitogen-activated protein kinase kinase kinase 7-interacting protein 3; NF-kappa-B-activating protein 1; TAK1-binding protein 3; TAB-3; TGF-beta-activated kinase 1-binding protein 3; TAB3; MAP3K7IP3

• Gene Name:

  TAB3

• UniProt:

  Q8N5C8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A partial length recombinant TAB3 protein (amino acids 1-350)

• Clonality:

  Polyclonal

• Tissue Specificity:

  Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript.

• Applications:

  WB

• Field of Research:

  Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, MAPK Pathway, NFKB Pathway, Nuclear Signaling, Nuclear Signaling Pathways, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Signaling Pathway, TLR Signaling

• Purification:

  Protein A Chromatography

• Concentration:

  0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Dilution:

  Western blot: 4-6 µg/ml

• Form:

  Liquid

• Function:

  Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor. .

• Molecular Weight:

  78683 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

• Fragment:

  Rabbit IgG

• Other Gene Names:

  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

• Protein Name:

  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3