Anti-WDR79 WRAP53 Monoclonal Antibody

• Description:

  Boster Bio Anti-WDR79 WRAP53 Monoclonal Antibody catalog # A04484. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Telomerase Cajal body protein 1; WD repeat-containing protein 79; WD repeat-containing protein WRAP53; WD40 repeat-containing protein antisense to TP53 gene; WRAP53; TCAB1, WDR79

• Gene Name:

  WRAP53

• UniProt:

  Q9BUR4

• Host:

  Mouse

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Purified recombinant human WDR79 protein fragments expressed in E.coli.

• Clonality:

  Monoclonal

• Tissue Specificity:

  Expressed in all tissues and cell lines examined. .

• Applications:

  WB

• Purification:

  Protein A purified

• Form:

  Liquid

• Function:

  Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs) . The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post- transcriptional level; it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage. .

• Molecular Weight:

  59309 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Telomerase Cajal body protein 1

• Subcellular Location:

  Nucleus, Cajal body. Cytoplasm.