Btk substrate peptide

• Description :

  Btk substrate peptide is a peptide substrate corresponding to residues 217-229 of human Bruton’s tyrosine kinase (Btk), of which the tyrosine at residue 223 is the major autophosphorylation site of Btk. Btk substrate peptide is used as a substrate in in vitro kinase assays to evaluate the activity of Btk or other tyrosine kinases[1].

• UNSPSC :

  12352209

• Target :

  Btk

• Type :

  Peptides

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/btk-substrate-peptide.html

• Smiles :

  O=C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCSC)C(N3[C@@H](CCC3)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

• Molecular Formula :

  C72H114N16O19S2

• Molecular Weight :

  1571.90

• References & Citations :

  [1]Bence, et al. "Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit." Nature 389.6648 (1997) : 296-299.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported