Btk substrate peptide

• Description:

  Btk substrate peptide is a peptide substrate corresponding to residues 217-229 of human Bruton’s tyrosine kinase (Btk), of which the tyrosine at residue 223 is the major autophosphorylation site of Btk. Btk substrate peptide is used as a substrate in in vitro kinase assays to evaluate the activity of Btk or other tyrosine kinases[1].

• UNSPSC:

  12352209

• Target:

  Btk

• Type:

  Peptides

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/btk-substrate-peptide.html

• Smiles:

  O=C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCSC)C(N3[C@@H](CCC3)C(N[C@@H](CCSC)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

• Molecular Formula:

  C72H114N16O19S2

• Molecular Weight:

  1571.90

• References & Citations:

  [1]Bence, et al. "Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit." Nature 389.6648 (1997) : 296-299.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported