Anti-Urocortin UCN Antibody

• Description:

  Boster Bio Anti-Urocortin UCN Antibody (Catalog# A01807-1) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  UCN; Urocortin

• Gene Name:

  UCN

• UniProt:

  P55089

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A peptide derived from human Urocortin. Immunogen sequence location: 71-120

• Clonality:

  Polyclonal

• Tissue Specificity:

  Keratinocytes in epidermis and the outer and inner root sheaths of hair follicles, epithelium of sebaceous and sweat glands, erector pili muscle, cutaneous blood vessel walls, cutaneous nerves and dermal mononuclear cells (PubMed:10690896) . Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) (at protein level) . Expressed in pituitary and adrenal glands (PubMed:10690896) . Detected in plasma cells in the lamia propria in colon mucosa (PubMed:15531481) .AS74

• Applications:

  IHC-P, IF (paraffin), ELISA

• Purification:

  The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

• Concentration:

  0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Function:

  Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) (PubMed:8612563) . Binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta (PubMed:8612563) . Plays a role in the establishment of normal hearing thresholds (By similarity) . Reduces food intake and regulates ghrelin levels in gastric body and plasma (By similarity) .

• Molecular Weight:

  13458 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Other Gene Names:

  Urocortin

• Subcellular Location:

  Secreted.