Anti-TANK Antibody

• Description:

  Boster Bio Anti-TANK Antibody catalog # A00445-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  TRAF family member-associated NF-kappa-B activator; TRAF-interacting protein; I-TRAF; TANK; ITRAF, TRAF2

• Gene Name:

  TANK

• UniProt:

  Q92844

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human TANK. AA range:171-220

• Tissue Specificity:

  Ubiquitous.

• Applications:

  WB

• Purification:

  Immunogen affinity purified

• Dilution:

  WB, 1:500-1:2000

• Form:

  Liquid

• Function:

  Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining them in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. .

• Molecular Weight:

  47816 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  TRAF family member-associated NF-kappa-B activator

• Subcellular Location:

  Cytoplasm.