Human Arylsulfatase A/ARSA ELISA Kit PicoKine®

• Background:

  Arylsulfatase A (or cerebroside-sulfatase) is an enzyme that breaks down sulfatides, namely cerebroside 3-sulfate into cerebroside and sulfate. In humans, arylsulfatase A is encoded by the ARSA gene. It is mapped to 22q13.33. The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

• Description:

  Human ARSA ELISA Kit PicoKine® (96 Tests) . Quantitate Human ARSA in cell culture supernatants, serum and plasma (heparin, EDTA, citrate) . Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Synonyms:

  Arylsulfatase A; ASA; Cerebroside-sulfatase; ARSA

• Gene Name:

  Arylsulfatase A

• UniProt:

  P15289

• Reactivity:

  Human

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: R19-A507

• Applications:

  ELISA

• Sample Type:

  Cell culture supernatants, serum and plasma (heparin, EDTA, citrate) .

• Detection Range:

  312 pg/ml - 20,000 pg/ml

• Sensitivity:

  <50 pg/ml

• Function:

  Hydrolyzes cerebroside sulfate.

• Storage Conditions:

  Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Other Gene Names:

  ARSA

• Subcellular Location:

  Endoplasmic reticulum. Lysosome.