Mouse APOH ELISA Kit PicoKine®

• Background:

  Apolipoprotein H (Apo-H), previously known as β2-glycoprotein I and beta-2 glycoprotein I, is a 38 kDa multifunctional apolipoprotein that in humans is encoded by the APOH gene. This gene is mapped to 11 E1; 11 71.8 Cm. Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.

• Description:

  Mouse APOH ELISA Kit PicoKine® (96 Tests) . Quantitate Mouse Apoh in cell culture supernatants, serum and plasma (heparin, EDTA) . Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.

• Synonyms:

  Beta-2-glycoprotein 1; APC inhibitor; Activated protein C-binding protein; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I; B2GPI; Beta (2) GPI; Apoh; B2gp1

• Gene Name:

  Apolipoprotein H

• UniProt:

  Q01339

• Reactivity:

  Mouse

• Cross Reactivity:

  There is no detectable cross-reactivity with other relevant proteins.

• Immunogen:

  Expression system for standard: NS0; Immunogen sequence: G20-C345

• Tissue Specificity:

  Expressed by the liver and secreted in plasma.

• Applications:

  ELISA

• Field of Research:

  Cardiovascular, Lipid Metabolism, Lipids/Lipoproteins, Metabolism, Signal Transduction

• Sample Type:

  Cell culture supernatants, serum and plasma (heparin, EDTA) .

• Detection Range:

  312 pg/ml - 20,000 pg/ml

• Sensitivity:

  <50 pg/ml

• Function:

  Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

• Storage Conditions:

  Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

• Other Gene Names:

  Apoh

• Subcellular Location:

  Secreted

• Protein Name:

  Beta-2-glycoprotein 1