Rat VE-Cadherin Cdh5 ELISA Kit PicoKine®

Rat VE-Cadherin Cdh5 ELISA Kit PicoKine®

• Background: Cadherin 5, type 2 or VE-cadherin also known as CD144, is a type of cadherin. It is encoded by the human gene CDH5. This gene is mapped to 19p14. VE-cadherin is a classical cadherin from the cadherin superfamily and the gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell–cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
• Description: Rat VE-Cadherin Cdh5 ELISA Kit PicoKine® (96 Tests). Quantitate Rat Cdh5 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 50pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Cadherin 5; Cdh5
• CAS Number: 7732-18-5
• Gene Name: cadherin 5
• Gene ID: 307618
• UniProt: F1M7E5
• Reactivity: Rat
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: D46 - Q599
• Applications: ELISA
• Sample Type: cell culture supernatants, serum and plasma (heparin, EDTA).
• Detection Range: 312 pg/ml - 20,000 pg/ml
• Sensitivity: <50 pg/ml
• : heparin or EDTA
• Function: Cadherins are calcium-dependent cell adhesion proteins.
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	399	410	443	467	429	26.92	6.2%
  Sample 2	1935	2194	2013	2122	2066	99.36	4.8%
  Sample 3	8758	8677	8447	8601	8620	114.65	1.3%

  *number of samples for each test n=16.
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Specificity: Natural and recombinant rat VE-Cadherin/CD144