Cinoxate-d3

• UNSPSC Description:

  Cinoxate-d3 is deuterium labeled Cinoxate. Cinoxate is a hypertrophic peroxisome proliferator activating receptor γ (PPARγ) agonist with Ki value of 18.0 μM. Cinoxate can be used to study obesity[1][2].

• Target Antigen:

  Isotope-Labeled Compounds; PPAR

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Others;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(OCCOCC)/C=C/C1=CC=C(OC([2H])([2H])[2H])C=C1

• Molecular Weight:

  253.31

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]An S, et al. Cheminformatic Read-Across Approach Revealed Ultraviolet Filter Cinoxate as an Obesogenic Peroxisome Proliferator-Activated Receptor γ Agonist. Chem Res Toxicol. 2024 Aug 2.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported