Mouse ACE2 ELISA Kit PicoKine®

Mouse ACE2 ELISA Kit PicoKine®

• Background: AngiotensinI-converting enzyme 2 (ACE 2) is a protein belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. By sequence similarity to a sequence in GenBank, this gene is mapped to Xp22.2. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
• Description: Mouse ACE2 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ace2 in cell culture supernatants, serum and plasma (heparin). Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Angiotensin-converting enzyme 2;3.4.17.23;ACE-related carboxypeptidase;Processed angiotensin-converting enzyme 2;Ace2;
• CAS Number: 7732-18-5
• Gene Name: Angiotensin-converting enzyme 2
• Gene ID: 70008
• UniProt: Q8R0I0
• Reactivity: Mouse
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: CHO; Immunogen sequence: Q18-T740
• Applications: ELISA
• Sensitivity: <10 pg/ml
• Function: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury. .
• : heparin
• Sample Type: cell culture supernatants, serum and plasma (heparin).
• Detection Range: 62.5 pg/ml - 4,000 pg/ml
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Calculated Molecular Weight: 92368 MW
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	146	150	152	149	149	2.16	1.4%
  Sample 2	538	544	526	551	539	9.17	1.7%
  Sample 3	1252	1287	1257	1185	1245	37.27	2.9%

  *number of samples for each test n=16.
• Specificity: Natural and recombinant mouse ACE2