Human TGF-Beta 3 ELISA Kit PicoKine®

Human TGF-Beta 3 ELISA Kit PicoKine®

• Background: Transforming growth factor beta 3 (TGF-beta 3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGF-beta 3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-beta 3, mammals develop a deformity known as acleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse. TGF-beta 3 also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. TGF-beta 3 activated Lef1 in the absence of beta-catenin (CTNNB1) via nuclear phospho-Smad2 and Smad4.
• Description: Human TGF-Beta 3 ELISA Kit PicoKine® (96 Tests). Quantitate Human TGFB3 in cell culture supernatants, serum, plasma (EDTA) and urine. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Transforming growth factor beta-3;TGF-beta-3;Latency-associated peptide;LAP;TGFB3;
• CAS Number: 7732-18-5
• Gene Name: Transforming growth factor beta-3
• Gene ID: 7043
• UniProt: P10600
• Reactivity: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: A301-S412
• Applications: ELISA
• Sensitivity: <10 pg/ml
• Function: Involved in embryogenesis and cell differentiation.
• : EDTA
• Sample Type: cell culture supernatants, serum, plasma (EDTA) and urine.
• Detection Range: 31.2 pg/ml - 2,000 pg/ml
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Calculated Molecular Weight: 47328 MW
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	66	60	63	72	65	4.43	6.8%
  Sample 2	244	241	250	232	241	6.49	2.6%
  Sample 3	776	841	916	907	860	56.48	6.5%

  *number of samples for each test n=16.
• Specificity: Natural and recombinant human TGF-beta 3