Human NT-4/NTF4/Neurotrophin-4 ELISA Kit PicoKine®

Human NT-4/NTF4/Neurotrophin-4 ELISA Kit PicoKine®

• Background: Neurotrophin-4 (NT-4), also known as neurotrophin-5 (NT-5), is a protein that in humans is encoded by the NTF4 gene. Human NT-4 as well as a human NT-4 pseudogene colocalize to chromosome 19 band q13.3. NT-4 is a member of a family of neurotrophic factors, the neurotrophins, that control survival and differentiation of vertebrate neurons (2-4). NT-4 is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. NT4 plays a physiological role essential for hippocampus- and amygdala-dependent long-term memory and hippocampal long-lasting LTP and that NT4 may be useful in the therapy of acquired disorders of learning and memory.
• Description: Human NT-4 ELISA Kit PicoKine® (96 Tests). Quantitate Human NTF4 in cell culture supernatants and serum. Sensitivity: 10pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Neurotrophin-4;NT-4;Neurotrophin-5;NT-5;Neutrophic factor 4;NTF4;NTF5;
• CAS Number: 7732-18-5
• Gene Name: Neurotrophin-4
• Gene ID: 4909
• UniProt: P34130
• Reactivity: Human
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: G81-A210
• Applications: ELISA
• Sample Type: cell culture supernatants and serum.
• Detection Range: 31.2 pg/ml - 2,000 pg/ml
• Sensitivity: <10 pg/ml
• Function: Target-derived survival factor for peripheral sensory sympathetic neurons.
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Calculated Molecular Weight: 22427 MW
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	94	99	93	89	93	3.56	3.8%
  Sample 2	234	212	207	213	216	10.35	4.7%
  Sample 3	888	924	870	895	894	19.44	2.1%

  *number of samples for each test n=16.
• Specificity: Natural and recombinant human NT-4