Mouse Neurotrophin-3 ELISA Kit PicoKine®

Mouse Neurotrophin-3 ELISA Kit PicoKine®

• Background: Neurotrophin-3 (NT-3) is a new member of the nerve growth factor gene family, which plays an important role in the development and maintenance of the vertebrate nervous system.NT-3 and its receptor, called neurotrophic tyrosine kinase receptor type 3 (Ntrk3; also called TrkC), are expressed early and throughout embryogenesis. NT-3 is one of five neurotrophin growth factors which shape the development of the nervous system by regulating neuronal survival and differentiation. NT-3 may be one of the central nervous system-derived factors that mediate neural crest (NC) cell proliferation in vivo. NT-3 has been mapped to human chromosome 12p and mouse chromosome 6.
• Description: Mouse Neurotrophin-3 ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Ntf3 in cell culture supernatants and serum. Sensitivity: 2pg/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.
• Synonyms: Neurotrophin-3;NT-3;HDNF;Nerve growth factor 2;NGF-2;Neurotrophic factor;Ntf3;Ntf-3;
• CAS Number: 7732-18-5
• Gene Name: Neurotrophin-3
• Gene ID: 18205
• UniProt: P20181
• Reactivity: Mouse
• Cross Reactivity: There is cross-reactivity with NT-4<2.5%, and no detectable cross-reactivity with any other cytokine.
• Immunogen: Expression system for standard: NS0; Immunogen sequence: Y139-T257
• Applications: ELISA
• Sample Type: cell culture supernatants and serum.
• Detection Range: 15.6 pg/ml - 1,000 pg/ml
• Sensitivity: <2 pg/ml
• Function: Seems to promote the survival of visceral and proprioceptive sensory neurons.
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Calculated Molecular Weight: 29588 MW
• Reproducibility:

  Lots	Lot 1 (pg/ml)	Lot 2 (pg/ml)	Lot 3 (pg/ml)	Lot 4 (pg/ml)	Mean (pg/ml)	Standard Deviation	CV (%)
  Sample 1	31	31	33	29	31	1.41	4.5%
  Sample 2	195	189	201	195	195	4.24	2.1%
  Sample 3	532	466	458	478	483	28.89	5.9%

  *number of samples for each test n=16.
• Specificity: Natural and recombinant mouse Neurotrophin-3