Mouse PON1 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

Mouse PON1 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

• Background: Serum paraoxonase/arylesterase 1 (PON1) also known as aromatic esterase 1 or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. The PON gene was mapped to chromosome 7q21-q22, and the mouse Pon1 gene was mapped to the proximal end of chromosome 6. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL).
• Description: Mouse PON1 ELISA Kit EZ-Set™ (DIY Antibody Pairs) (antibody pairs and standards for assay development). Quantitate Mouse Pon1 in cell culture supernatants, serum and plasma (heparin).
• Synonyms: Serum paraoxonase/arylesterase 1; PON 1
• CAS Number: 7732-18-5
• Gene Name: paraoxonase 1
• Gene ID: 18979
• UniProt: P52430
• Reactivity: Mouse
• Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
• Immunogen: Expression system for standard: E.Coli; Immunogen sequence: A30-L355
• Applications: ELISA
• Detection Range: 156 pg/ml - 10,000 pg/ml
• : heparin
• Sample Type: cell culture supernatants, serum and plasma (heparin).
• Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.
• Storage Conditions: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
• Specificity: Natural and recombinant mouse PON1