2-Phenylpropionic acid

• Description :

  2-Phenylpropionic acid is an intermediate in the metabolism of alpha-Methylstyrene. 2-Phenylpropionic acid covalently binds to rat liver protein. 2-Phenylpropionic acid can be used in the research of nonsteroidal anti-inflammatory agents[1][2][3].

• UNSPSC :

  12352005

• Hazard Statement :

  H314

• Target :

  Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/2-Phenylpropionic_acid.html

• Concentration :

  10mM

• Purity :

  99.91

• Solubility :

  DMSO : ≥ 100 mg/mL|H2O : 4.35 mg/mL (ultrasonic)

• Smiles :

  C1=C(C(C(O)=O)C)C=CC=C1

• Molecular Formula :

  C9H10O2

• Molecular Weight :

  150.18

• Precautions :

  H314

• References & Citations :

  [1]De Costa KS, et al. Metabolism and disposition of alpha-methylstyrene in rats. Drug Metab Dispos. 2001 Feb;29 (2) :166-71.|[2]Li C, et al. Enantioselective covalent binding of 2-phenylpropionic Acid to protein in vitro in rat hepatocytes. Chem Res Toxicol. 2002 Nov;15 (11) :1480-7. |[3]Li C, et al. In vivo mechanistic studies on the metabolic activation of 2-phenylpropionic acid in rat. J Pharmacol Exp Ther. 2003 Apr;305 (1) :250-6.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [492-37-5]