Human LINGO1 Protein, Llama IgG2b Fc Tag

Human LINGO1 Protein, Llama IgG2b Fc Tag

• Background: Predicted to enable epidermal growth factor receptor binding activity. Predicted to act upstream of or within generation of neurons and protein kinase B signaling. Predicted to be located in plasma membrane. Predicted to be active in extracellular matrix and extracellular space. Implicated in autosomal recessive non-syndromic intellectual disability and glaucoma.
• Description: Human LINGO1 Protein, Llama IgG2b Fc Tag (LIO-H5256) is expressed from human 293 cells (HEK293). It contains AA Cys 42 - Thr 561 (Accession # Q96FE5-1).
• Specifications: This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 86.9 kDa. The protein migrates as 130-170 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression Region: Cys 42 - Thr 561
• Host: HEK 293
• Target: LINGO1
• Conjugation: Unconjugated
• Tag: C-LlamaFc(LlamaIgG2b)
• Source: Human
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 0.05 EU per μg
• Purity: 95%
• Format: Powder
• Buffer: PBS, pH7.4
• Additives: Trehalose
• Molecular Weight: 86.9 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C