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Omeprazole-d3

CAT: 0804-HY-B0113S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0113S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Omeprazole-d3 (H 16868-d3) is deuterium labeled Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].
CAS Number
922731-01-9
Product Name Alternative
H 16868-d3
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Autophagy; Bacterial; Proton Pump
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Autophagy; Membrane Transporter/Ion Channel
Field of Research
Cancer; Infection; Metabolic Disease
Purity
98.99
Solubility
DMSO : 125mg/mL (ultrasonic)
Smiles
CC(C(OC)=C(C)C=N1)=C1CS(C2=NC3=CC=C(OC([2H])([2H])[2H])C=C3N2)=O
Molecular Formula
C17H16D3N3O3S
Molecular Weight
348.43
Precautions
H315, H319, H335
References & Citations
[1]Li XQ, et al. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32 (8) :821-7.|[2]Jonkers D, et al. Omeprazole inhibits growth of gram-positive and gram-negative bacteria including Helicobacter pylori in vitro. J Antimicrob Chemother. 1996 Jan;37 (1) :145-50.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported