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KUNG65

CAT: 0804-HY-162767Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162767Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KUNG65 is a selective inhibitor of Grp94, with a target Kd of 540 nM and at least 73 fold selectivity vs. the other Hsp90 isoforms[1].
CAS Number
2144469-30-5
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kung65.html
Smiles
ClC1=C(O)C=C(O)C(C(OC)=O)=C1CCC2=C(CC3=CC=C(F)C=C3)C=CC=C2
Molecular Formula
C23H20ClFO4
Molecular Weight
414.85
References & Citations
[1]Kyler Pugh, et al. Investigation of the site 2 pocket of Grp94 with KUNG65 benzamide derivatives. Bioorg Med Chem Lett. 2024 Oct 1:111:129893.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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