Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2

Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2

• CAS Number: 400716-78-1
• UNSPSC Description: Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2 is a cathepsin D substrate, that can be used for cathepsin D FRET assay[1].
• Target Antigen: Cathepsin
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/ac-glu-asp-edans-lys-pro-ile-leu-phe-phe-arg-leu-gly-lys-dabcyl-glu-nh2.html
• Solubility: H2O
• Smiles: O=S(O)(C1=CC=CC2=C1C=CC=C2NCCNC(C[C@H](NC([C@@H](NC(C)=O)CCC(O)=O)=O)C(N[C@@H](CCCCN)C(N3[C@@H](CCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCNC(C4=CC=C(C=C4)/N=N/C5=CC=C(C=C5)N(C)C)=O)C(N[C@H](C(N)=O)CCC(O)=O)=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)CC7=CC=CC=C7)=O)=O)=O)=O)=O)=O)=O
• Molecular Weight: 2132.48
• References & Citations: [1]Eketjäll S, et al. AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics. J Alzheimers Dis. 2016;50(4):1109-23.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported