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SORL1 Antibody

CAT: 0013-GTR18124071Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18124071Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SORL1 Antibody
Product Name Alternative
SORL1, LR11, sortilin-related receptor, L (DLR class) A repeats-containing, LRP9, SORLA, gp250, SorLA-1, mosaic protein LR11, C11orf32, FLJ21930, FLJ39258, sortilin-related receptor containing LDLR class A repeats
UniProt
Q92673
Reactivity
Human
Immunogen
The immunogen for this antibody is: C-TGFSDDVPMVIA
Target
SORL1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
500 ug/mL
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Peptide ELISA: antibody detection limit dilution 1:32000.Immunofluorescence: Strong expression of the protein seen in A431 and HepG2 cells. Recommended concentration: 10μg/mL.
Prediction Reactivity
Bovine, Canine, Mouse, Rat
Tested Applications
ELISA, IF
NCBI Accession Number
NP_003096.1
Host or Source
Goat
Preservative
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

UniProtKB · Q92673

Sortilin-related receptor

SORL_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92673
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SORL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2RNX7, Q92856
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Alzheimer diseaseAmyloidosisDisease variantNeurodegeneration

Cellular component

Cell membraneCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusMembraneSecreted

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Biological process

EndocytosisProtein transportTransport

Molecular function

Receptor

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