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RO6806051

CAT: 0804-HY-161702-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161702-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RO6806051 (compound 12) is a potent dual inhibitor of fatty acid binding protein 4 and 5 (FABP4 and FABP5), with Ki values of 0.011 and 0.086 μM for hFABP4 and hFABP5, respectively. It exhibits good selectivity and favorable absorption, distribution, metabolism, and excretion (eADME) properties[1].
CAS Number
1433901-75-7
UNSPSC
12352005
Target
FABP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ro6806051.html
Purity
99.84
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
ClC1=CC2=C(N=C(N3CCCCC3)C(C4=NN=NN4)=C2C5=CC=CC=C5)C=C1
Molecular Formula
C21H19ClN6
Molecular Weight
390.87
References & Citations
[1]Kühne H, et al. Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors. Bioorg Med Chem Lett. 2016 Oct 15;26 (20) :5092-5097.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19234126-01RO6806051

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